Monthly Archives: February 2016

Two Challenges of Technology Transfer – Part 1, the National Systems.

Two documents have led me to describe two types of challenges facing the technology transfer of academic institutions.
– First, at a macro-economic level, the challenge comes from the various possible administrative structures, but also the complexity of the operations. The report Transfert et Valorisation dans le PIA (in French) by Bruno Rostand compares the national policies of Germany and the United Kingdom to that of France.
– Secondly, at the micro-economic level, the journal Nature published the article Keys to the kingdom with the subtitle, What you should know about your technology transfer office. I will come back to this in my next post.

Mise en page 1

The report of Bruno Rostand addresses the challenges that France meets after having established regional structures for technology transfer, the “SATT”. He notes that Germany has built a similar system with its “PVA” in the Länder. In both cases, there is a goal of financial independence which seems difficult to achieve if not unrealistic, despite the existence of public subsidies. In Germany, two of these companies have even filed for bankruptcy in Lower Saxony in 2006 and Berlin in 2013.

Why such difficulties? Because the returns on investment have not been up to the expectations. For example, approximately €10M euros have been invested each year in the form of public funds in Germany, but revenues remained much lower. In addition the regional structure has its limitations, as it is difficult to gain expertise in all areas of technology.

The United Kingdom has a different situation. The state has been a marginal actor and technology transfer was organized either by universities (Cambridge, Oxford, Imperial College) or by private structures close to venture capital (IP group) which organically helped in structuring technology transfer. Through externalization, these organizations have become private organizations, which have become rich in financial and human resources. At Oxford, ISIS employs 80 people for £14.5m in revenue in 2014. Imperial innovation has been publicly traded since 2006, employs 45 people and generated a profit of £27M in 2014. Imperial innovation has expanded its initial base in collaborating with other universities. Finally, the IP Group has agreements with over 15 universities for a profit of £9.5M in 2014. The report shows very different philosophies, whether public or private, with profitability as an end or not, with an obvious entrepreneurial dimension in the UK. if the focus on start-ups is important, this will lead to different structures, including maturation funds and incubators.

The report also shows that a licensing policy and a policy to support the creation of start-ups are very different. Finally, the new TT structures often have the sole responsibility of the development and maturation of IP, while research collaborations with industry remain the responsibility of universities. This separation could be a weakness when the two topics are linked.

A sensitive issue is that of exclusivity that can create tension when TT management is pooled over many universities. Some universities want to maintain some autonomy, especially in areas where the technical competence of the TT structure seems weak to them. Another sensitive issue is that of the structure by region while a transregional structure by field of expertise might be more appropriate. (The report also addresses research partnerships and international cooperation that I will not discuss here.)

In the final part, Rostand shows the complexity of the challenges. One must first define the mission of technology transfer which can be for profit or not. Externalization seems to be a trend in the three countries, but it has its advantages and disadvantages. It also seems that there is a lot of instability and fluctuations in funding cycles, which does not help to make an analysis of the transfer tools. The report also addresses the issue of human resources (types of skills and experience), another subject which may be related to the available resources of these organizations.

The only personal comment I make here is about my slight frustration at not having found in the report (which is extremely informative) an analysis of the US situation. The country of liberalism and private universities have very few external technology transfer structures, let alone for-profit. I have in mind WARF at University of Wisconsin-Madison – www.warf.org) while revenues of TT in the USA are significantly higher than in Europe. The explanation could simply come from a far more dynamic private innovation, regardless of all the systems in place.

Street Art in Florence

There is probably no city in the world without some Street Art. After my discoveries of Banksy, Space Invader all over the world and the Mirror Mosaic in Pully, here are some pictures from Florence.

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Florence_.K_2

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This artist seems to be known via his signature, .K and a couple of other web pages describe his or her work: Exit/Enter and The Elusive “.K”. The next pictures include him again but also famous Clet Abraham who is acting all over the world.

Florence_.K_clet

Here is a little more.

Florence_.K_more

Here is another link of his work in Florence: Florence street sign art by Clet. Finally what about this poetic work?

Florence_Blub

Emerging Science and Technologies, why so many promises? (Part 4)

This is my final post about what I have learned from Sciences et technologies émergentes, pourquoi tant de promesses? (For the record here are the links to part 1, part 2 and part 3).

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The last chapters of this excellent book try to explore ways to solve the problem of excessive promises that have become a system. In Chapter IV.2, it is question of “désorcèlement” (the closest term I found would be “disenchanted”); I read it as a critical analysis of the vocabulary used by those who promise. The chapter speaks at length of the transhumanist movement, the promise of promises! “[…] Describe how these actors certainly produce, but especially divert away, reconfigure and amplify these promises […] in front of passive and naive consumers.” [Page 261] and later “[but] transhumanists are first activists, mostly neither engineers nor practitioners […] attempting answers to questions not asked or badly expressed, […] hence a really caricatural corpus,” to the point of talking about a “cult” (quoting Jean-Pierre Dupuy), “a muddled, often questionable thinking.” [Page 262]

In Chapter IV.3, the authors explore unconventional approaches, a possible sign of disarray to “scientifically” react to the promises. For example, they have contributed to the creation of a comic book to answer another comic which wanted to popularize and promote synthetic biology.

Adventures_Synthetic_Biology

The final chapter explores scenarios that may follow the explosion of promises, like the idea of ​​increasing the number of Nobel Prize. New promises?!! More concretely, the author shows that the initial promises are not followed in practice: “The wait & see phenomenon in investment, or lack of innovation, is less known, though widespread: the effect of general and diffuse promises maintains the interest of players but too much uncertainty holds back investment in cycles of concrete promises-requirements.” [Page 297] “A game is at work which continues as long as the players follow the rules, […] they are prisoners of the game. […] They may also leave it if the right circumstances occur and then the game collapses.” [Page 298]

In conclusion, beyond a very rich description of many examples of scientific and technical promises, the authors have shown how a system of promises was built through interactions between the various stakeholders (the researchers themselves, the (political, social and economic) decision makers who fund them, and the general public which hopes and feels anxiety). The relationship to time, not only the future but also the present and the past, is beautifully described, in addition to a desire for eternity. And finally, we mostly discover that the promises have led to numerous debates that were perhaps, if not entirely, useless, as we could have known that the promises can not be kept, even from the moment they were created…

Emerging Science and Technologies, why so many promises? (Part 3)

This is my third article about the book Sciences et technologies émergentes, pourquoi tant de promesses? After the general considerations on the system of promises, the book presents contributions describing specific areas:

I.3: nanotechnologies
II.1: semiconductors through Moore’s Law
II.2: big ata
II.3: digital Humanities
III.1: neurosciences and psychiatry
III.2: The Human Brain Project (HBP)
III.3: personalized medicine
III.4: biodiversity and nanomedicine
IV.1: assisted reproduction
IV.2: regenerative medicine

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Each chapter is interesting for the curious reader as it shows the dynamics between promises and expectations of stakeholders (researchers, politicy makers, general public). The chapter about the HBP is particularly interesting in the description of the disconnection between content and form. “How was it possible that the HBP “won the competition” despite the lack of evidence to establish pragmatically the scientific relevance and the legitimacy of its ambitious organizational goals? We develop the hypothesis that this deficit, criticized afterwards, was both hidden and compensated by the production of promises shaped to anticipate and / or respond effectively to the political, economic, social and health-realted stakes on the agenda of the “challenges to come”. [Page 166] The credibility of the HBP sealed by this decision has been built […] following an adaptation process and reciprocal validations in the double register of the politicization of science and the scientification of politics. In other words, we show that one of the important conditions of this credibility was the successful co-production of a strategic congruence between [scientific] promises and the agenda of policy issues. [Page 171] The connection between knowledge of the brain and forms of social life took place mainly in the domain of discourse. […] In this contrasting situation, discursive inflation around the brain and neuroscience seems to be the consequence of a lack of evidence, as if it had overcome, positively or negatively, the differences between the present and the future, the proven and the possible, the absence and the desire. This regular feature of big science projects has resulted in the development and implementation of a prophetic rhetoric that seeks to anticipate the possibility of a better future by borrowing to the notions of hope and promise.” [Page 176-77]

I come back to a quote from chapter 3 that is essential to me as a conclusion to this new post: The real progress of techno-science will less come from their ability to keep promises than from their ability to do without them, to inherit critically from the era of great technological promise. This is not to break an idol, but to learn how to inherit. [Page 111]

Emerging Science and Technologies, why so many promises? (Part 2)

(A word of caution: my English is reaching its limits in trying to analyze a demanding book, written in French. I apologize in advance for the very awkward wording…)

So just one day after my article describing Chapter 1 of Emerging Science and Technologies, why so many promises?, here comes an analysis of the second chapter, where the relation to time is analyzed, as well as presentism, futurism and the role of time in the promise system. There is the nice following passage:

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Since The New Atlantis, futuristic speculations have accompanied the development of modern science. And in the twentieth century, Jean Perrin has sealed a new alliance between science and hope. But for him, it is science that preceded and provoked hope while now, it is rather hope that drives research. Technosciences reverse, in fact, the order of the questions that was following the three critiques of Kant: “What can I know?” – the issue addressed in Critique of Pure Reason – then the question “What can I do?” – treated in the Critique of Practical Reason – finally the question “What can I expect?” – discussed in the Critique of Judgment. In contrast, in the current scientific policies, one determines what to do and what we can possibly acquire as knowledge by identifying the hopes and promises. (Page 50)

Yet there is a paradox already expressed in the first chapter between futurism with the terms of promise, foresight and prophecy that project us and presentism particularly marked by the memory that freezes the past and transforms the future as a threat that no longer enlightens neither the past nor the present. To the point of talking about a future presentification…

The chapter also deals with the question of the future as a shock, a time “crisis” due to the acceleration. To the feeling of the misunderstanding and helplessness, is added the experience of frustration and stress caused by the accelerated pace of life, the disappointment of a promise related to modernity, where techniques were supposed to save time, to emancipate.

Another confusion: the features of planning and roadmap which are typical of technology projects slipped into research projects where is used the term of production of knowledge, while in research, it is impossible to guarantee a result. But the author shows through two examples, that this development is complex.

In the case of nanotechnology, there has been roadmap with the first two relatively predictable stages of component production followed by a third stage on more speculative systems crowned by a fourth stage which speaks of emergence, and all this by also “neglecting contingency, serendipity and possible bifurcations,” not to predict, but to “linearize the knowledge production”. The roadmap predicts the unexpected by announcing an emergence, combining a reassuring scenario of control which helps in inspiring confidence and with at the same time an emerging scenario, to create dreams. (Pages 55-56)

In the case of synthetic biology “despite a clear convergence with nanotechnology,” the rapid development occurs without any roadmap. “A common intention – the design of the living – gathers these research paths.” And it is more to redo the past (“3.6 billion years of genetic code”) than to imagine the future. The future becomes abstract and it comes as proofs of concept. And the author adds that in normal science in the sense of Kuhn, these proofs of concepts would have fallen into oblivion. The paradox is that there is no question of right or wrong, but of designing without any needed functionality.

In the first case, “prediction or forecasting are convened as the indispensable basis for a strategy based on rational choice”, “the future looks to the present. “In the second case, there is the question of “towing the present” and “fleeing out of time.” We unite and mobilize without any necessary aim. The future is virtual, abstract, and devoid of culture and humanity; the life of the augmented human looks more like eternal rest …

Ultimately, the economy of promises remains riveted on the present either by making the future a reference point to guide action in the present, or it is seeking to perpetuate the present.

Chapters three and four are less theoretical, describing on one hand new examples in the field of nanotechnology and on the other, how Moore’s Law became a law when it was initially a prospective vision of progress in semiconductor. Perhaps soon a follow-up about the next chapters…

Emerging Science and Technologies, why so many promises? (Part 1)

Sciences et technologies émergentes, pourquoi tant de promesses? (Emerging Science and Technologies, why so many promises?) is the title of a book (in French only) from a group of authors under the direction of Marc Audétat, a political scientist and researcher at the Sciences -Society Interface of the University of Lausanne. This is not an easy reading book, it is quite demanding, but it raises important questions.

I have already reported on this blog about books that speak of a certain crisis of science, for example in The Crisis and the American model (in French), about the books “La Science à bout de Souffle” or “The University bubble. Should we pursue the American dream?” or in The Trouble With…, a book by Lee Smolin, not to mention the most violent criticism of the promises of technology by Peter Thiel in Technology = Salvation.

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This new book explores the promises related to science and technology to the point of talking about an economy of promises. This is a collective work which does not make it an easy reading, but the diversity of points of views is certainly an asset. I have not finished reading it and I will certainly come back to it. In the first chapter, P.-B. Joly describes the system of techno-scientific promises. He begins by introducing the concepts of Imaginary and Vision [Page 33] This “couple of concepts takes into account how various sources of inspiration are involved in the technical creation. […] The Imaginary gives an almost tangible appearance to concepts and ideals that are a priori devoid of it … [and becomes] a common sense that founds the action into society. […] The concept of Vision is close to that of Imaginary, but on a smaller scale. It is akin to that of “rational myth” used to analyze the dynamics of collective action in changing contexts. […] Coalitions of actors form around these visions of a prospective order and contribute to their dynamics. […] If we accept this conceptual distinction between Imaginaries (at large scales – the Nation – and in the long term) and Visions (at a level of coalitions of actors and active over periods of medium length) then comes the question of the interaction between the two.”

“Unlike Visions and Imaginaries, for which the content of technical arrangements is essential, what is essential for the techno-scientific promises is the creation of a relation, as well as a time horizon of expectations. […] Promises are essential in technology creation, because they enable innovators to legitimize their projects, to mobilize resources and to stabilize their environment. […] Any techno-scientific promise must convince a large audience that it determines a better future than the alternatives, even if the realization of the promise requires major, sometimes painful changes.” (The author mentions the history of electricity or the green revolution as the solution to world hunger)

“Our concept of techno-scientific promises has been systematized and became in the last forty years the governance of the new techno-sciences (biotechnology and genomics, nanotechnology, neuroscience, synthetic biology, geo -engineering, etc.) The construction of a techno-scientific promise meets two conflicting constraints: the constraint Radical Novelty and that of Credibility. […] (And I interpret that) for this request to be credible, one must disqualify alternatives. [Furthermore] For a scientific theory to be credible, its validity is neither necessary nor sufficient. […] The techno-scientific promises must have the support of a circle of specialists. Otherwise, they cannot resist the opposition manifested either in scientific arenas, or in public arenas. An extreme version is observed when the specialists refer to natural laws to justify the inevitability of technological change. (Examples are Moore’s Law and Gabor’s Law.) Thus, in principle, generic promises are not subject to validity tests.”

Finally, this intensification is reinforced by three complementary elements [page 39]:
– the future is more a threat than a source of hope;
– research and innovation are often presented as the only way to solve problems;
– the research stakeholders should demonstrate their societal impacts.

This leads to pathologies [pages 40-43]:
– the myth of a public victim of irrational fears and to be educated becomes an intangible scheme;
– the promises turn into bubbles;
– the radical novelty and uncertainty create conflicting discourses, sources of mistrust because the effects of such radicalism is not predictable so that through experimentation, the technologists become sorcerer’s apprentices and society, a laboratory;
– finally promises lead to endless discussions on fictions, on issues that may have nothing to do with the reality of research.

In conclusion Joly thinks this promises system is one of the enemies of the future because of the clear separation it creates between those who make the promise and those who are supposed to accept it. The recognition of this regime and therefore these problems is a prerequisite imperative.

After reading the first chapter, I remembered the societal concerns of Cynthia Fleury, about whom I have already said a few things in a digression in the article On France Culture, Transhumanism is Science Fiction. Our democratic societies are in crisis, and the distrust of politics as well as of experts has never been stronger. The issue of research and innovation is a component of this crisis. I am eager to discover the rest of this very interesting (and important) work …

The Rise and Fall of BlackBerry

Very interesting article in the very good ParisTech Review: The Rise and Fall of BlackBerry. The article shows how disruption is more and more threatening not only for established companies but also fast growing start-ups.

Blackberry was founded in 1984 as Research in Motion by two young engineering students from the University of Waterloo – Mike Lazaridis – and the University of Windsor – Douglas Fregin. They were about 23 years-old. Eight years later, an experienced business man, James Balsillie, would join, invest some of his money ($250k) and become Co-CEO with Lazaridis. RIM funded a lot of its initial activity with partners (Ontario New Ventures – $15k; General Motors – $600k, Ericsson, – $300k, University of Waterloo – $100k, Ontario local development – $300k) so that it raised investor money in 1995 only, including Intel in 1997. The company went public on the Toronto Stock Exchange in October 1997 and then on Nasdaq in 1999.

ParisTech-Blackberry-en

As the authors notice, “though BlackBerry has less than 1% of the smartphone market share today, it once had more than 50%. […] In this era of disruption, the mother of disruption stories is the BlackBerry story. A company that introduced the BlackBerry in 1998 became a $20 billion company from nothing in less than a decade. Then four or five years later, it was back down to a $3 billion company, gasping for breath. It’s not only a disruption story; it is a story of the speed of the technology race today.”

They explain how Lazaridis was a visionary when mobile phones had to be simple devices and how he failed a few years later: “The pivotal moment is January 2007 when Steve Jobs walks onto the stage in San Francisco and holds up that shiny glass object that we all [now] know and love so much, and says, “This is an iPhone.” […] The really compelling part of the BlackBerry story is how they reacted that day. Over in Mountain View, California, you had the folks at Google under a secret project. One was for a new keyboard phone and the other was for a touch screen phone that was going to be run on Android. The minute they watched that live, streaming on the internet, they realized that their project keyboard was dead, and they immediately shifted everything to the touch screen phone…. Mike Lazaridis looked at this announcement, looked at what Steve Jobs was offering, and said, “This is an impossibility.” Again, the conservative engineer brought up on conservation said, “The networks won’t be able to carry this. It’s an impossibility. It’s illogical that anyone would even propose this.” He was right for the first two years. Remember all the dropped calls, all the frustrations, all the lawsuits against Apple and the carriers. It didn’t work…. But then it did, and RIM got it wrong. Two years is a lifetime at a technology rate, and by the time they realized what a serious threat it was, they were at that point followers.”

Blackberry was (still is) the success story of the University of Waterloo and Wikipedia mentions how much Lazaridis has given back to his alma mater: in 2000, Lazaridis founded the Perimeter Institute for Theoretical Physics. He has donated more than $170 million to the institute. In 2002, Lazaridis founded the Institute for Quantum Computing (IQC) at the University of Waterloo. He, with wife Ophelia, has donated more than $100 million to IQC since 2002. This looks very similar to what Logitech and Daniel Borel are to EPFL (where I work). You should read the full article and I conclude here with my usual cap. table…

Blackberry CapTable